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Assess platelet count with clinical interpretation and bleeding/clotting risk
Also written as 10⁹/L (same numeric value)
| Clinical Situation | Threshold | Notes |
|---|---|---|
| Prophylaxis (stable patient) | 10 K/µL | Standard threshold for chemotherapy-induced |
| Active bleeding | 50 K/µL | Target for most bleeding situations |
| Minor surgery / procedures | 50 K/µL | Lumbar puncture, central line placement |
| Major surgery | 50-100 K/µL | Depends on procedure type |
| Neurosurgery / eye surgery | 100 K/µL | Critical bleeding areas |
Platelets (thrombocytes) are cell fragments from megakaryocytes that circulate for 8-10 days. They are essential for hemostasis, forming plugs at injury sites and activating the coagulation cascade.
MPV measures platelet size (7.5-11.5 fL). Young platelets are larger and more active. High MPV suggests increased production. Low MPV may indicate bone marrow suppression.
Platelet count may be normal but function impaired by aspirin, NSAIDs, uremia, or inherited disorders (von Willebrand disease). Bleeding time or PFA-100 assess function.